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Probiotics are for general support and should not be used to treat a potential bowel obstruction or severe gastroparesis (stomach paralysis)

Moreover, participants receive weekly check-ins that spur weight loss efforts better than anything at the Rent-A-Drill-Sergeant shop.

Quick disclosure - as a pharmaceutical and biotech equity research analyst at one of the largest banks for the past 5 years, I spent lots of time analyzing one of the two companies mentioned above, which means I was partly responsible for our teams view of which pharma companies presented a good investment opportunity for institutional investors who were our clients and had access to our research

An important nuance from the NEJM paper: The paper notes that the mechanism "may further amplify heart rate elevation" through the glucagon receptor, while acknowledging this is consistent with the known pharmacology rather than proven in direct mechanistic studies specific to retatrutide